Cancer-miRNA Regulatory Network

Compendium of miRNA Target Genes

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CA Bladder Dyrskjot Cluster Number 40 (195 genes) This page contains all miRNA mediated regulation and functional enrichment for CA Bladder Dyrskjot cluster number 40. Information about bladder cancer can be found on Wikipedia, and further information about the "CA Bladder Dyrskjot" dataset can be found in Dyrskjot et al., 2004. Inferred miRNA Mediated Regulation Weeder-miRvestigator PITA TargetScan zzz999 zzz999 hsa-mir-548d-3p Gene Ontology Enrichment GO ID GO Term Annotated Genes in Cluster GO:0000077 DNA damage checkpoint 8 GO:0000084 S phase of mitotic cell cycle 10 GO:0000216 M/G1 transition of mitotic cell cycle 7 GO:0000278 mitotic cell cycle 23 GO:0000375 RNA splicing, via transesterification reactions 14 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 14 GO:0000398 nuclear mRNA splicing, via spliceosome 14 GO:0001510 RNA methylation 4 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 91 GO:0006369 termination of RNA polymerase II transcription 5 GO:0006396 RNA processing 32 GO:0006397 mRNA processing 23 GO:0006403 RNA localization 9 GO:0006487 protein N-linked glycosylation 7 GO:0006508 proteolysis 24 GO:0006511 ubiquitin-dependent protein catabolic process 19 GO:0006520 cellular amino acid metabolic process 14 GO:0006521 regulation of cellular amino acid metabolic process 8 GO:0006605 protein targeting 13 GO:0006886 intracellular protein transport 21 GO:0006913 nucleocytoplasmic transport 13 GO:0006915 apoptosis 36 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 7 GO:0008104 protein localization 35 GO:0008152 metabolic process 145 GO:0008219 cell death 38 GO:0008380 RNA splicing 21 GO:0009056 catabolic process 36 GO:0009057 macromolecule catabolic process 27 GO:0009451 RNA modification 6 GO:0010498 proteasomal protein catabolic process 16 GO:0012501 programmed cell death 37 GO:0015031 protein transport 34 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport 9 GO:0016032 viral reproduction 16 GO:0016070 RNA metabolic process 66 GO:0016071 mRNA metabolic process 36 GO:0016072 rRNA metabolic process 6 GO:0016265 death 38 GO:0018196 peptidyl-asparagine modification 7 GO:0018279 protein N-linked glycosylation via asparagine 7 GO:0019941 modification-dependent protein catabolic process 19 GO:0022403 cell cycle phase 24 GO:0022613 ribonucleoprotein complex biogenesis 12 GO:0030163 protein catabolic process 21 GO:0030433 ER-associated protein catabolic process 4 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 8 GO:0031167 rRNA methylation 2 GO:0031570 DNA integrity checkpoint 8 GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint 7 GO:0031575 mitotic cell cycle G1/S transition checkpoint 7 GO:0033036 macromolecule localization 42 GO:0033238 regulation of cellular amine metabolic process 8 GO:0034613 cellular protein localization 22 GO:0034660 ncRNA metabolic process 13 GO:0042254 ribosome biogenesis 7 GO:0042981 regulation of apoptosis 29 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process 16 GO:0043170 macromolecule metabolic process 118 GO:0043414 macromolecule methylation 6 GO:0043632 modification-dependent macromolecule catabolic process 19 GO:0044237 cellular metabolic process 136 GO:0044238 primary metabolic process 135 GO:0044248 cellular catabolic process 34 GO:0044257 cellular protein catabolic process 19 GO:0044260 cellular macromolecule metabolic process 112 GO:0044265 cellular macromolecule catabolic process 24 GO:0044419 interspecies interaction between organisms 16 GO:0045184 establishment of protein localization 34 GO:0046907 intracellular transport 33 GO:0048193 Golgi vesicle transport 10 GO:0050657 nucleic acid transport 9 GO:0050658 RNA transport 9 GO:0051028 mRNA transport 7 GO:0051169 nuclear transport 13 GO:0051236 establishment of RNA localization 9 GO:0051320 S phase 10 GO:0051325 interphase 18 GO:0051329 interphase of mitotic cell cycle 18 GO:0051340 regulation of ligase activity 8 GO:0051351 positive regulation of ligase activity 8 GO:0051352 negative regulation of ligase activity 8 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 8 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 8 GO:0051438 regulation of ubiquitin-protein ligase activity 8 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 8 GO:0051443 positive regulation of ubiquitin-protein ligase activity 8 GO:0051444 negative regulation of ubiquitin-protein ligase activity 8 GO:0051603 proteolysis involved in cellular protein catabolic process 19 GO:0051641 cellular localization 40 GO:0051649 establishment of localization in cell 38 Overlap Between miRNA Target Genes and Enriched Gene Ontology Annotations miRNA Method GO ID GO Term Overlap GO Annotated Genes Cluster Size miRNA Targets Genes P-Value hsa-mir-548d-3p TargetScan GO:0000077 DNA damage checkpoint 1 8 195 84 0.9265139 hsa-mir-548d-3p TargetScan GO:0000084 S phase of mitotic cell cycle 3 10 195 84 0.6969054 hsa-mir-548d-3p TargetScan GO:0000216 M/G1 transition of mitotic cell cycle 1 7 195 84 0.882498 hsa-mir-548d-3p TargetScan GO:0000278 mitotic cell cycle 6 23 195 84 0.9388428 hsa-mir-548d-3p TargetScan GO:0000375 RNA splicing, via transesterification reactions 7 14 195 84 0.2046272 hsa-mir-548d-3p TargetScan GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 7 14 195 84 0.2046272 hsa-mir-548d-3p TargetScan GO:0000398 nuclear mRNA splicing, via spliceosome 7 14 195 84 0.2046272 hsa-mir-548d-3p TargetScan GO:0001510 RNA methylation 2 4 195 84 0.2141094 hsa-mir-548d-3p TargetScan GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 42 91 195 84 0.1693896 hsa-mir-548d-3p TargetScan GO:0006369 termination of RNA polymerase II transcription 3 5 195 84 0.1098251 hsa-mir-548d-3p TargetScan GO:0006396 RNA processing 14 32 195 84 0.3880159 hsa-mir-548d-3p TargetScan GO:0006397 mRNA processing 11 23 195 84 0.2367398 hsa-mir-548d-3p TargetScan GO:0006403 RNA localization 4 9 195 84 0.3305607 hsa-mir-548d-3p TargetScan GO:0006487 protein N-linked glycosylation 2 7 195 84 0.6483003 hsa-mir-548d-3p TargetScan GO:0006508 proteolysis 5 24 195 84 0.9854765 hsa-mir-548d-3p TargetScan GO:0006511 ubiquitin-dependent protein catabolic process 5 19 195 84 0.9064634 hsa-mir-548d-3p TargetScan GO:0006520 cellular amino acid metabolic process 2 14 195 84 0.9798436 hsa-mir-548d-3p TargetScan GO:0006521 regulation of cellular amino acid metabolic process 1 8 195 84 0.9265139 hsa-mir-548d-3p TargetScan GO:0006605 protein targeting 6 13 195 84 0.2986995 hsa-mir-548d-3p TargetScan GO:0006886 intracellular protein transport 9 21 195 84 0.4132173 hsa-mir-548d-3p TargetScan GO:0006913 nucleocytoplasmic transport 6 13 195 84 0.2986995 hsa-mir-548d-3p TargetScan GO:0006915 apoptosis 17 36 195 84 0.2282765 hsa-mir-548d-3p TargetScan GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 1 7 195 84 0.882498 hsa-mir-548d-3p TargetScan GO:0008104 protein localization 18 35 195 84 0.09893154 hsa-mir-548d-3p TargetScan GO:0008152 metabolic process 62 145 195 84 0.4964257 hsa-mir-548d-3p TargetScan GO:0008219 cell death 19 38 195 84 0.1267296 hsa-mir-548d-3p TargetScan GO:0008380 RNA splicing 10 21 195 84 0.2477243 hsa-mir-548d-3p TargetScan GO:0009056 catabolic process 10 36 195 84 0.9705264 hsa-mir-548d-3p TargetScan GO:0009057 macromolecule catabolic process 9 27 195 84 0.8132952 hsa-mir-548d-3p TargetScan GO:0009451 RNA modification 3 6 195 84 0.2209702 hsa-mir-548d-3p TargetScan GO:0010498 proteasomal protein catabolic process 3 16 195 84 0.9665133 hsa-mir-548d-3p TargetScan GO:0012501 programmed cell death 18 37 195 84 0.1722802 hsa-mir-548d-3p TargetScan GO:0015031 protein transport 18 34 195 84 0.07143759 hsa-mir-548d-3p TargetScan GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport 4 9 195 84 0.3305607 hsa-mir-548d-3p TargetScan GO:0016032 viral reproduction 8 16 195 84 0.1979572 hsa-mir-548d-3p TargetScan GO:0016070 RNA metabolic process 30 66 195 84 0.2631952 hsa-mir-548d-3p TargetScan GO:0016071 mRNA metabolic process 15 36 195 84 0.498946 hsa-mir-548d-3p TargetScan GO:0016072 rRNA metabolic process 2 6 195 84 0.5201012 hsa-mir-548d-3p TargetScan GO:0016265 death 19 38 195 84 0.1267296 hsa-mir-548d-3p TargetScan GO:0018196 peptidyl-asparagine modification 2 7 195 84 0.6483003 hsa-mir-548d-3p TargetScan GO:0018279 protein N-linked glycosylation via asparagine 2 7 195 84 0.6483003 hsa-mir-548d-3p TargetScan GO:0019941 modification-dependent protein catabolic process 5 19 195 84 0.9064634 hsa-mir-548d-3p TargetScan GO:0022403 cell cycle phase 6 24 195 84 0.9567318 hsa-mir-548d-3p TargetScan GO:0022613 ribonucleoprotein complex biogenesis 3 12 195 84 0.8422452 hsa-mir-548d-3p TargetScan GO:0030163 protein catabolic process 5 21 195 84 0.9535189 hsa-mir-548d-3p TargetScan GO:0030433 ER-associated protein catabolic process 0 4 195 84 0.8974653 hsa-mir-548d-3p TargetScan GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 1 8 195 84 0.9265139 hsa-mir-548d-3p TargetScan GO:0031167 rRNA methylation 1 2 195 84 0.1842982 hsa-mir-548d-3p TargetScan GO:0031570 DNA integrity checkpoint 1 8 195 84 0.9265139 hsa-mir-548d-3p TargetScan GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint 1 7 195 84 0.882498 hsa-mir-548d-3p TargetScan GO:0031575 mitotic cell cycle G1/S transition checkpoint 1 7 195 84 0.882498 hsa-mir-548d-3p TargetScan GO:0033036 macromolecule localization 21 42 195 84 0.1155673 hsa-mir-548d-3p TargetScan GO:0033238 regulation of cellular amine metabolic process 1 8 195 84 0.9265139 hsa-mir-548d-3p TargetScan GO:0034613 cellular protein localization 9 22 195 84 0.4924763 hsa-mir-548d-3p TargetScan GO:0034660 ncRNA metabolic process 3 13 195 84 0.8899429 hsa-mir-548d-3p TargetScan GO:0042254 ribosome biogenesis 2 7 195 84 0.6483003 hsa-mir-548d-3p TargetScan GO:0042981 regulation of apoptosis 12 29 195 84 0.4960813 hsa-mir-548d-3p TargetScan GO:0043161 proteasomal ubiquitin-dependent protein catabolic process 3 16 195 84 0.9665133 hsa-mir-548d-3p TargetScan GO:0043170 macromolecule metabolic process 51 118 195 84 0.4221137 hsa-mir-548d-3p TargetScan GO:0043414 macromolecule methylation 3 6 195 84 0.2209702 hsa-mir-548d-3p TargetScan GO:0043632 modification-dependent macromolecule catabolic process 5 19 195 84 0.9064634 hsa-mir-548d-3p TargetScan GO:0044237 cellular metabolic process 58 136 195 84 0.511772 hsa-mir-548d-3p TargetScan GO:0044238 primary metabolic process 56 135 195 84 0.6984568 hsa-mir-548d-3p TargetScan GO:0044248 cellular catabolic process 9 34 195 84 0.9766565 hsa-mir-548d-3p TargetScan GO:0044257 cellular protein catabolic process 5 19 195 84 0.9064634 hsa-mir-548d-3p TargetScan GO:0044260 cellular macromolecule metabolic process 49 112 195 84 0.3572995 hsa-mir-548d-3p TargetScan GO:0044265 cellular macromolecule catabolic process 8 24 195 84 0.7897588 hsa-mir-548d-3p TargetScan GO:0044419 interspecies interaction between organisms 12 16 195 84 0.00144059 hsa-mir-548d-3p TargetScan GO:0045184 establishment of protein localization 18 34 195 84 0.07143759 hsa-mir-548d-3p TargetScan GO:0046907 intracellular transport 15 33 195 84 0.3087927 hsa-mir-548d-3p TargetScan GO:0048193 Golgi vesicle transport 6 10 195 84 0.0758669 hsa-mir-548d-3p TargetScan GO:0050657 nucleic acid transport 4 9 195 84 0.3305607 hsa-mir-548d-3p TargetScan GO:0050658 RNA transport 4 9 195 84 0.3305607 hsa-mir-548d-3p TargetScan GO:0051028 mRNA transport 3 7 195 84 0.3491692 hsa-mir-548d-3p TargetScan GO:0051169 nuclear transport 6 13 195 84 0.2986995 hsa-mir-548d-3p TargetScan GO:0051236 establishment of RNA localization 4 9 195 84 0.3305607 hsa-mir-548d-3p TargetScan GO:0051320 S phase 3 10 195 84 0.6969054 hsa-mir-548d-3p TargetScan GO:0051325 interphase 3 18 195 84 0.9859795 hsa-mir-548d-3p TargetScan GO:0051329 interphase of mitotic cell cycle 3 18 195 84 0.9859795 hsa-mir-548d-3p TargetScan GO:0051340 regulation of ligase activity 1 8 195 84 0.9265139 hsa-mir-548d-3p TargetScan GO:0051351 positive regulation of ligase activity 1 8 195 84 0.9265139 hsa-mir-548d-3p TargetScan GO:0051352 negative regulation of ligase activity 1 8 195 84 0.9265139 hsa-mir-548d-3p TargetScan GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 1 8 195 84 0.9265139 hsa-mir-548d-3p TargetScan GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 1 8 195 84 0.9265139 hsa-mir-548d-3p TargetScan GO:0051438 regulation of ubiquitin-protein ligase activity 1 8 195 84 0.9265139 hsa-mir-548d-3p TargetScan GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 1 8 195 84 0.9265139 hsa-mir-548d-3p TargetScan GO:0051443 positive regulation of ubiquitin-protein ligase activity 1 8 195 84 0.9265139 hsa-mir-548d-3p TargetScan GO:0051444 negative regulation of ubiquitin-protein ligase activity 1 8 195 84 0.9265139 hsa-mir-548d-3p TargetScan GO:0051603 proteolysis involved in cellular protein catabolic process 5 19 195 84 0.9064634 hsa-mir-548d-3p TargetScan GO:0051641 cellular localization 20 40 195 84 0.121072 hsa-mir-548d-3p TargetScan GO:0051649 establishment of localization in cell 19 38 195 84 0.1267296

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